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GSK’s Linerixibat Shows Promise in Treating PBC-Related Itch

Story Highlights
  • GSK’s GLISTEN trial showed linerixibat significantly improves cholestatic pruritus in PBC.
  • The trial results suggest linerixibat could address a major symptom of PBC, improving patient quality of life.
  • Looking for the best stocks to buy? Follow the recommendations of top-performing analysts.
GSK’s Linerixibat Shows Promise in Treating PBC-Related Itch

Don’t Miss TipRanks’ Half-Year Sale

An announcement from GlaxoSmithKline ( (GSK) ) is now available.

GSK announced positive results from its GLISTEN phase III trial of linerixibat, an investigational drug for treating cholestatic pruritus in patients with primary biliary cholangitis (PBC). The trial met its primary and key secondary endpoints, showing significant improvements in itch severity and itch-related sleep interference compared to placebo. These findings, presented at the European Association for the Study of the Liver Congress 2025, highlight linerixibat’s potential to address a major symptom of PBC, offering hope for patients with limited treatment options.

Spark’s Take on GSK Stock

According to Spark, TipRanks’ AI Analyst, GSK is a Neutral.

GSK’s overall stock score reflects stable financial performance with slight pressure on margins and cash flow. Technical analysis shows a stable momentum with no significant overbought or oversold signals. The company’s valuation is reasonable, supported by a healthy dividend yield. The recent earnings call highlighted positive growth prospects in specialty medicines, despite some challenges in vaccine sales and macroeconomic concerns. These factors collectively contribute to a moderate stock score.

To see Spark’s full report on GSK stock, click here.

More about GlaxoSmithKline

GSK is a global biopharma company focused on uniting science, technology, and talent to advance disease treatment. The company is actively researching treatments for liver diseases, including primary biliary cholangitis (PBC), chronic hepatitis B, alcohol-related liver disease, and metabolic dysfunction-associated steatohepatitis.

Average Trading Volume: 5,588,434

Technical Sentiment Signal: Buy

Current Market Cap: $78.26B

For an in-depth examination of GSK stock, go to TipRanks’ Stock Analysis page.

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