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An announcement from Genprex ( (GNPX) ) is now available.
On April 21, 2026, Genprex announced a new Sponsored Research Agreement with The University of Texas MD Anderson Cancer Center to study biomarkers that may predict patient response to its Reqorsa Gene Therapy in lung cancer. Preclinical work has highlighted TROP2 and PTEN as potential biomarkers, which could sharpen patient selection for the company’s Acclaim-1 and Acclaim-3 clinical trials and potentially improve clinical outcomes.
The company reported that its Acclaim-1 Phase 1/2 trial in late-stage NSCLC combining Reqorsa with Tagrisso has advanced into Phase 2a after Phase 1 showed Reqorsa was generally well tolerated, with no dose-limiting toxicities and early signs of efficacy, including a durable partial response. Genprex also said its Acclaim-3 Phase 1/2 trial in extensive-stage SCLC combining Reqorsa with Tecentriq has moved into Phase 2 after a clean safety profile in Phase 1 and an unconfirmed partial remission lasting more than 18 months for one patient, underscoring the potential clinical promise of its gene therapy platform.
Separately, Genprex released an updated investor presentation, available on its website, for use in meetings with investors, analysts and other stakeholders on or after April 21, 2026. The new data and research collaboration reinforce the company’s positioning as an emerging player in gene therapy-based oncology, with ongoing clinical validation efforts that could influence future treatment paradigms in lung cancer.
More about Genprex
Genprex, Inc. is a clinical-stage biopharmaceutical company focused on developing gene therapies for oncology, with a lead candidate, Reqorsa Gene Therapy (quaratusugene ozeplasmid), in development for non-small cell lung cancer and small cell lung cancer. The company collaborates with major cancer centers and large pharma partners to test Reqorsa in combination with approved therapies such as AstraZeneca’s Tagrisso and Genentech’s Tecentriq.
Average Trading Volume: 796,370
Technical Sentiment Signal: Sell
Current Market Cap: $11.58M
Learn more about GNPX stock on TipRanks’ Stock Analysis page.