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Fractyl Health, Inc. ( (GUTS) ) just unveiled an announcement.
On December 2, 2025, Fractyl Health announced positive results from its REVEAL-1 Cohort study, showing that participants maintained stable weight and glycemic control six months after discontinuing GLP-1 therapy and undergoing a single Revita procedure. The study highlights Revita’s potential as a first-in-class therapy for post-GLP-1 weight maintenance, with no serious adverse events reported. The company is advancing towards multiple clinical readouts in 2026, indicating significant progress in its REMAIN weight maintenance program.
The most recent analyst rating on (GUTS) stock is a Hold with a $1.50 price target. To see the full list of analyst forecasts on Fractyl Health, Inc. stock, see the GUTS Stock Forecast page.
Spark’s Take on GUTS Stock
According to Spark, TipRanks’ AI Analyst, GUTS is a Neutral.
Fractyl Health’s overall stock score is primarily impacted by its precarious financial situation, characterized by high leverage and persistent losses. Despite this, the company shows promising clinical progress and a strong cash position, which are positive indicators for future growth. Technical analysis suggests bullish momentum, but the stock may be overbought in the short term. Valuation remains a concern due to negative profitability metrics.
To see Spark’s full report on GUTS stock, click here.
More about Fractyl Health, Inc.
Fractyl Health, Inc. is a metabolic therapeutics company focused on pioneering new approaches to treat metabolic diseases such as obesity and type 2 diabetes. The company aims to transform treatment from chronic symptomatic management to durable disease-modifying therapies, targeting the root causes of these conditions. Fractyl Health is based in Burlington, MA, and has a robust intellectual property portfolio with numerous patents.
Average Trading Volume: 3,423,170
Technical Sentiment Signal: Hold
Current Market Cap: $213.8M
See more data about GUTS stock on TipRanks’ Stock Analysis page.

