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Eledon Pharmaceuticals Advances in Transplant Trials

Eledon Pharmaceuticals Advances in Transplant Trials

Eledon Pharmaceuticals, Inc. ( (ELDN) ) has released its Q2 earnings. Here is a breakdown of the information Eledon Pharmaceuticals, Inc. presented to its investors.

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Eledon Pharmaceuticals, Inc. is a clinical-stage biotechnology company focused on developing immune-modulating therapies for life-threatening conditions, with its lead investigational product, tegoprubart, targeting the CD40 Ligand pathway. The company recently reported its second quarter 2025 financial results, highlighting significant progress in its clinical trials and financial performance.

Eledon Pharmaceuticals announced promising data from its ongoing Phase 1b trial of tegoprubart, demonstrating stable kidney function in transplant patients. The company is on track to release topline results from its Phase 2 BESTOW trial in kidney transplantation by November 2025. Additionally, Eledon has made strides in other transplant indications, including islet cell and liver allotransplantation, showcasing tegoprubart’s potential to improve transplant outcomes.

Financially, Eledon reported cash, cash equivalents, and short-term investments totaling $107.6 million as of June 30, 2025, down from $140.2 million at the end of 2024. The company’s R&D expenses increased to $20.3 million in the second quarter of 2025, reflecting its ongoing commitment to advancing its clinical programs. Despite a net loss of $11.2 million for the quarter, this marks a significant improvement from the $44.9 million loss in the same period last year.

Looking ahead, Eledon Pharmaceuticals remains focused on achieving key milestones, including the anticipated results from the Phase 2 BESTOW trial and further exploration of tegoprubart’s applications in various transplant settings. The company expects its current financial resources to support operations through the end of 2026, positioning it well for continued progress in its clinical endeavors.

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