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Cyclerion Therapeutics ( (CYCN) ) has issued an update.
On December 1, 2025, Akebia Therapeutics announced the initiation of Phase 2 clinical trials for treating focal segmental glomerulosclerosis (FSGS) using Praliciguat, a drug licensed from Cyclerion Therapeutics. This development triggers a $1.0 million regulatory milestone payment to Cyclerion upon the dosing of the first patient in the U.S., expected in 2026.
Spark’s Take on CYCN Stock
According to Spark, TipRanks’ AI Analyst, CYCN is a Neutral.
Cyclerion Therapeutics’ overall stock score is primarily influenced by its financial difficulties, including consistent net losses and negative cash flows, despite having a solid equity position and no debt. The technical analysis provides a slightly more optimistic view with some bullish momentum, but the valuation remains unattractive due to ongoing financial challenges. The lack of earnings call or corporate events data means these factors did not affect the score.
To see Spark’s full report on CYCN stock, click here.
More about Cyclerion Therapeutics
Average Trading Volume: 692,099
Technical Sentiment Signal: Sell
Current Market Cap: $6.2M
For an in-depth examination of CYCN stock, go to TipRanks’ Overview page.