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Compugen Secures $90 Million in a Strategic Royalty Monetization Deal with AstraZeneca

Story Highlights
  • Compugen monetized rilvegostomig royalties for $65M upfront and $25M potential milestone payment.
  • The deal boosts Compugen’s financial position, extending its cash runway to 2029 to advance cancer therapies.
  • Looking for the best stocks to buy? Follow the recommendations of top-performing analysts.
Compugen Secures $90 Million in a Strategic Royalty Monetization Deal with AstraZeneca

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An announcement from Compugen ( (CGEN) ) is now available.

On December 16, 2025, Compugen Ltd. amended its license agreement with AstraZeneca, monetizing a portion of future royalties from rilvegostomig for an upfront payment of $65 million and a potential milestone payment of $25 million. This strategic transaction strengthens Compugen’s financial position, extending its cash runway to 2029, allowing funds to be allocated towards advancing its innovative immuno-oncology pipeline, including internal and partnered programs. Retaining the majority of future royalties, Compugen preserves long-term upside from the potential success of rilvegostomig, developed by AstraZeneca as a promising cancer immunotherapy drug, which is undergoing robust Phase 3 trials across various types of cancer.

The most recent analyst rating on (CGEN) stock is a Buy with a $4.00 price target. To see the full list of analyst forecasts on Compugen stock, see the CGEN Stock Forecast page.

Spark’s Take on CGEN Stock

According to Spark, TipRanks’ AI Analyst, CGEN is a Neutral.

Compugen’s overall stock score is primarily influenced by its financial performance and technical analysis. The company’s strategic partnerships and potential future milestones provide some optimism, but current financial challenges and valuation concerns weigh heavily on the score.

To see Spark’s full report on CGEN stock, click here.

More about Compugen

Compugen Ltd. is a clinical-stage therapeutic discovery and development company specializing in cancer immunotherapies powered by its AI/ML predictive computational discovery platform, Unigen™. The company develops innovative immuno-oncology drug candidates including COM902, an anti-TIGIT antibody, and COM701, an anti-PVRIG antibody, with programs targeting biological pathways to activate the immune system against cancer. Headquartered in Israel, Compugen’s shares are listed on Nasdaq and the Tel Aviv Stock Exchange under the ticker symbol CGEN.

Average Trading Volume: 398,776

Technical Sentiment Signal: Strong Sell

Current Market Cap: $139.4M

For detailed information about CGEN stock, go to TipRanks’ Stock Analysis page.

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