Cellectis Reveals Promising Cancer Therapy Breakthrough

Cellectis SA (CLLS) has released an update.

Cellectis SA, a clinical-stage biopharmaceutical company, has published research showcasing its breakthrough SMART DUAL CAR T-cell therapy designed to combat challenging solid tumors. The innovative therapy utilizes TALEN gene-editing technology to create allogeneic CAR T-cells targeting cancer-associated fibroblasts and tumor-associated antigens, demonstrating promising results in mice models without the previously concerning off-tumor toxicity. This advancement could mark a significant step in effectively treating solid tumors with CAR T-cell therapies.

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