Cardinal Health ((CAH)) announced an update on their ongoing clinical study.
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Study Overview: The study titled Real-world Study of Patients With Human Papillomavirus-positive Recurrent/ Metastatic Oropharyngeal Squamous Cell Carcinoma Treated With First Line Pembrolizumab or Nivolumab With or Without Chemotherapy aims to evaluate the effectiveness of pembrolizumab and nivolumab in treating HPV-positive oropharyngeal squamous cell carcinoma (OPSCC). This study is significant as it provides real-world evidence to compare with clinical trial data, enhancing the understanding of treatment benefits and informing future research.
Intervention/Treatment: The study tests the drugs pembrolizumab and nivolumab, used either as monotherapy or in combination with chemotherapy. These treatments target HPV-positive OPSCC, aiming to assess their effectiveness in real-world settings.
Study Design: This observational study follows a cohort model with a retrospective time perspective. It focuses on collecting data from patients already treated with the specified interventions, without any allocation or masking involved.
Study Timeline: The study began on January 8, 2025, with its primary completion and last update submitted on September 8, 2025. These dates are crucial as they mark the progress and recent updates of the study, indicating its completion and readiness for data analysis.
Market Implications: The completion of this study could influence Cardinal Health’s stock performance by providing valuable insights into the effectiveness of pembrolizumab and nivolumab. Positive results may boost investor confidence and position Cardinal Health favorably against competitors in the oncology market.
The study is completed, and further details are available on the ClinicalTrials portal.