Bristol-Myers Squibb Company ((BMY)) announced an update on their ongoing clinical study.
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Bristol-Myers Squibb Company is conducting a Phase 3 study titled ‘EXCALIBER-Maintenance’ to evaluate the effectiveness of iberdomide maintenance therapy compared to lenalidomide maintenance therapy in patients with newly diagnosed multiple myeloma following autologous stem cell transplantation. The study aims to determine which treatment offers better outcomes for patients, potentially setting a new standard in maintenance therapy for this condition.
The study involves two drugs: iberdomide, an experimental treatment, and lenalidomide, an active comparator. Iberdomide is being tested in three different doses to assess its efficacy and safety as a maintenance therapy option.
This interventional study is designed with a randomized, parallel assignment model and is open-label, meaning no masking is involved. The primary purpose is to evaluate treatment effectiveness, providing clear insights into the potential benefits of iberdomide over the current standard, lenalidomide.
The study began on June 22, 2023, and is currently recruiting participants. The last update was submitted on August 20, 2025. These dates are crucial as they indicate the study’s progress and timeline for potential results, which are yet to be submitted.
For investors, this study could significantly impact Bristol-Myers Squibb’s stock performance. A positive outcome may enhance the company’s market position in the oncology sector, potentially affecting investor sentiment favorably. Competitors in the multiple myeloma treatment space may also feel the ripple effects of this study’s results.
The study is ongoing, with further details available on the ClinicalTrials portal.