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Biotest AG’s Trimodulin Trial: A Potential Game-Changer for Severe Pneumonia Treatment

Biotest AG’s Trimodulin Trial: A Potential Game-Changer for Severe Pneumonia Treatment

Biotest (0N6Z) ((GB:0N6Z)), Biotest AG ((GB:0N70)) announced an update on their ongoing clinical study.

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Biotest AG is currently conducting a Phase III clinical trial titled ‘Efficacy and Safety of Trimodulin (BT588) in Subjects With Severe Community-acquired Pneumonia (sCAP).’ The study aims to evaluate the efficacy and safety of Trimodulin as an adjunctive treatment to the standard of care in adult patients with severe community-acquired pneumonia who are on invasive mechanical ventilation. This trial is significant as it explores potential advancements in treating severe pneumonia, a condition with substantial morbidity and mortality.

The intervention being tested is Trimodulin, a human IgM, IgA, IgG solution administered intravenously. It is intended to serve as an adjunctive treatment to the standard of care, potentially enhancing patient outcomes in severe pneumonia cases.

The study is designed as a randomized, placebo-controlled, double-blind, multi-center trial. Participants are randomly assigned to receive either Trimodulin or a placebo, with neither the participants nor the care providers aware of the assignments. The primary purpose of the study is treatment-focused.

The study began on September 9, 2023, and is currently recruiting participants. The primary completion and estimated completion dates are yet to be announced. The last update was submitted on July 22, 2025, indicating ongoing progress in the trial.

This clinical trial update could have significant implications for Biotest AG’s stock performance and investor sentiment. Success in this trial may enhance Biotest’s market position in the pharmaceutical industry, particularly in the treatment of severe pneumonia. Investors should monitor the trial’s progress and outcomes, as they could influence Biotest’s competitive standing and financial performance.

The study is ongoing, with further details available on the ClinicalTrials portal.

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