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The latest update is out from Assembly Biosciences ( (ASMB) ).
On June 25, 2025, Assembly Biosciences announced positive topline results from a Phase 1b clinical trial evaluating ABI-4334, a next-generation capsid assembly modulator, in participants with chronic hepatitis B virus infection. The trial demonstrated favorable safety, tolerability, and pharmacokinetics, supporting once-daily oral dosing. The results showed significant antiviral activity, with mean plasma HBV DNA reductions consistent across different dosage cohorts. These findings support the potential of ABI-4334 to inhibit viral replication and cccDNA formation, crucial for HBV treatment regimens. The completion of the trial triggers an opt-in point for collaboration with Gilead Sciences, Inc., which could impact future development and commercialization efforts.
The most recent analyst rating on (ASMB) stock is a Buy with a $29.00 price target. To see the full list of analyst forecasts on Assembly Biosciences stock, see the ASMB Stock Forecast page.
Spark’s Take on ASMB Stock
According to Spark, TipRanks’ AI Analyst, ASMB is a Neutral.
The most significant factor affecting Assembly Biosciences’ stock score is its poor financial performance, marked by an absence of revenue, persistent losses, and negative cash flows, which raise concerns about its profitability and liquidity. Although technical analysis suggests strong momentum, this is overshadowed by the company’s financial instability. The valuation score is low due to the negative P/E ratio, indicating ongoing financial challenges.
To see Spark’s full report on ASMB stock, click here.
More about Assembly Biosciences
Assembly Biosciences is a biotechnology company focused on developing innovative small-molecule therapeutics aimed at treating serious viral diseases, including herpesvirus, hepatitis B virus (HBV), and hepatitis delta virus (HDV) infections.
Average Trading Volume: 25,580
Technical Sentiment Signal: Buy
Current Market Cap: $130.6M
See more insights into ASMB stock on TipRanks’ Stock Analysis page.