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Arovella Showcases CLDN18.2 CAR-iNKT Solid Tumour Data at AACR

Story Highlights
  • Arovella unveiled pre-clinical CLDN18.2 CAR-iNKT data showing effective killing of pancreatic and gastric cancer cells in vitro.
  • The AACR presentation boosts Arovella’s visibility in solid tumour immunotherapy, supporting its IL-12-TM armoured iNKT platform expansion.
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Arovella Showcases CLDN18.2 CAR-iNKT Solid Tumour Data at AACR

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Arovella Therapeutics Limited ( (AU:ALA) ) has shared an announcement.

Arovella Therapeutics presented new pre-clinical data on its CLDN18.2-targeting CAR-iNKT cell therapy at the American Association for Cancer Research annual meeting in San Diego. The poster detailed how CLDN18.2 CAR-iNKT cells effectively killed CLDN18.2-positive pancreatic and gastric cancer cells in vitro, underscoring the potential of the company’s IL-12-TM armoured, allogeneic iNKT platform to expand its presence in solid tumour immunotherapy and reinforce its profile among cancer researchers and industry stakeholders.

Management highlighted the strong performance of the CLDN18.2 construct and the added benefit from incorporating IL-12-TM, signalling continued investment in generating further data to support future development. By showcasing this program at a major global cancer research forum, Arovella gains scientific visibility and validation that could help attract partners, talent and capital as it broadens its pipeline beyond blood cancers into difficult-to-treat solid tumours.

More about Arovella Therapeutics Limited

Arovella Therapeutics is an Australian biotechnology company developing an invariant Natural Killer T (iNKT) cell therapy platform to treat blood cancers and solid tumours. Its lead product, ALA-101, is an allogeneic CAR19-iNKT cell therapy targeting CD19-positive cancers, with an accepted IND from the U.S. FDA, and it is also advancing CLDN18.2-targeting and IL-12-TM armouring technologies for solid tumours.

Average Trading Volume: 1,054,821

Technical Sentiment Signal: Sell

Current Market Cap: A$104M

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