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Amplia Deepens Next & Bio Collaboration to Test Narmafotinib–kRAS Combo in Pancreatic Cancer

Story Highlights
  • Amplia extends its collaboration with Korea’s Next & Bio to study narmafotinib with experimental kRAS inhibitors in patient-derived pancreatic cancer models.
  • Promising early data and the new combination studies are intended to bolster narmafotinib’s clinical and partnering prospects in hard-to-treat pancreatic cancer.
  • Looking for the best stocks to buy? Follow the recommendations of top-performing analysts.
Amplia Deepens Next & Bio Collaboration to Test Narmafotinib–kRAS Combo in Pancreatic Cancer

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Amplia Therapeutics ( (AU:ATX) ) has shared an announcement.

Amplia Therapeutics has entered a second phase of its preclinical research collaboration with Korean drug screening specialist Next & Bio to further investigate the effects of its FAK inhibitor narmafotinib in combination with experimental kRAS inhibitors on patient-derived pancreatic cancer cells. The extension follows encouraging initial data showing narmafotinib’s activity against kRAS-mutant pancreatic cancer models, and the partners will now explore potential synergistic effects with kRAS inhibitors, a new class of drugs under development for several solid tumours. Amplia sees this next stage as an opportunity to strengthen its scientific case for combination therapies in hard-to-treat pancreatic cancer, enhance the clinical and commercial prospects of narmafotinib and potentially broaden partnering opportunities, while Next & Bio leverages its advanced patient-derived cell platform to support the development of new treatment options in an area of high unmet medical need.

The most recent analyst rating on (AU:ATX) stock is a Hold with a A$0.12 price target. To see the full list of analyst forecasts on Amplia Therapeutics stock, see the AU:ATX Stock Forecast page.

More about Amplia Therapeutics

Amplia Therapeutics Limited is an Australian pharmaceutical company developing a pipeline of Focal Adhesion Kinase (FAK) inhibitors for cancer and fibrosis, with a particular focus on fibrotic cancers such as pancreatic and ovarian cancer. Its lead candidate, narmafotinib (AMP945), is a highly potent and selective FAK inhibitor currently in clinical trials for advanced pancreatic cancer, where it has already shown improved response rates and progression-free survival when combined with standard chemotherapies.

Average Trading Volume: 1,083,167

Technical Sentiment Signal: Sell

Current Market Cap: A$64.13M

See more insights into ATX stock on TipRanks’ Stock Analysis page.

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