Akeso, Inc. ((HK:9926)) announced an update on their ongoing clinical study.
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Akeso, Inc. is conducting a Phase Ia clinical study titled ‘A Phase Ia Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Anti-tumor Efficacy of AK146D1 for Injection, an Anti-Trop2/Nectin4 Bispecific Antibody-drug Conjugate, in Patients With Advanced Solid Tumors.’ The study aims to assess the safety, tolerability, pharmacokinetics, and preliminary anti-tumor efficacy of AK146D1 in patients with advanced solid tumors, marking a significant step in cancer treatment research.
The intervention being tested is AK146D1 for injection, a bispecific antibody-drug conjugate targeting Trop2 and Nectin4, designed to treat advanced solid tumors by leveraging its dual-targeting mechanism to enhance anti-tumor activity.
This interventional study follows a sequential intervention model with no masking, focusing on treatment as its primary purpose. The allocation is non-randomized, allowing for a clear assessment of AK146D1’s effects.
The study began on March 16, 2025, with the latest update submitted on July 14, 2025. These dates are crucial as they indicate the study’s progression and ongoing recruitment status, which is vital for stakeholders tracking the development timeline.
The update on this study could positively influence Akeso’s stock performance by bolstering investor confidence in its innovative cancer treatment pipeline. As the biotech industry is highly competitive, advancements in clinical trials can significantly impact market dynamics and investor sentiment.
The study is currently ongoing, with further details available on the ClinicalTrials portal.