Ace hedge fund manager Cathie Wood’s ARK Invest ETFs (exchange-traded funds) reported several notable trades for Wednesday, September 17, 2025, highlighting a clear focus on biotech and gene-editing names. The ARK Innovation ETF (ARKK) made the day’s largest move, purchasing 339,924 shares of CRISPR Therapeutics (CRSP) worth about $20.8 million. ARKK also bought 491,127 shares of Beam Therapeutics (BEAM) for $11.2 million. Both stocks have been steady targets for ARK in recent weeks, underscoring Wood’s conviction in genomic medicine.
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Alongside these buys, the ARK Genomic Revolution ETF (ARKG) acquired 398,934 shares of Atai Life Sciences (ATAI) for $1.85 million. ARKG also picked up 22,754 shares of Arcturus Therapeutics (ARCT), a company focused on RNA medicines, valued at $411,000. In addition, ARKK expanded its stake in Intellia Therapeutics (NTLA) with a 211,618-share purchase worth $2.6 million.
Other Notable Buys Across ARK Funds
Beyond biotech, ARK spread capital across several sectors. The ARK Autonomous Technology and Robotics ETF (ARKQ) and the ARK Space Exploration ETF (ARKX) jointly added 10,508 shares of AeroVironment (AVAV) for about $2.8 million. ARKQ alone also acquired 5,164 shares of Baidu (BIDU) valued at $639,000.
The ARK Next Generation Internet ETF (ARKW) boosted exposure to Robinhood Markets (HOOD), purchasing 33,783 shares worth nearly $4 million. ARKQ also bought 88,335 shares of Pony AI (PONY), valued at $1.5 million. Smaller trades included 36,328 shares of Bullish (BLSH) across ARKK and ARKW, totaling $1.87 million, and 9,209 shares of L3Harris Technologies (LHX) for $2.62 million.
Wood Cuts Holdings in KTOS, ROKU, and Tempus AI
On the sell side, ARK reduced its stake in Kratos Defense & Security Solutions (KTOS), offloading 131,177 shares across ARKQ and ARKX for more than $10 million. The ARKK ETF also trimmed 5,000 shares of Roku (ROKU), worth $489,550, and 8,850 shares of Tempus AI (TEM) for about $770,000.
Here’s how these stocks perform on TipRanks’ Stock Comparison Tool:
