Leap Therapeutics, Amaze Holdings, and Aspire Biopharma Holdings are the 3 Penny Stocks to watch on November 17, 2025, based on TipRanks’ Penny Stock Screener tool. Penny stocks are defined as stocks that trade at or below $5 per share and have a market capitalization below $300 million.
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The Penny Stock Screener enables investors to identify stocks using various filters such as Sector, Price Target Upside, Smart Score, Analyst Consensus, Dollar Volume, and Price Change.
We leveraged the tool to identify the top three penny stocks with the highest Dollar Volume as of market close on November 14, 2025. Dollar Volume refers to the total value of shares traded in a day, calculated by multiplying the number of shares traded by the stock’s price.

Leap Therapeutics (LPTX) – Leap Therapeutics is a biopharmaceutical company dedicated to creating innovative therapies for cancer treatment. On November 14, LPTX had a Dollar Volume of $723.85 million, while its share price rocketed more than 56%.
The company’s stock has been climbing after it announced several major updates last week. Leap Therapeutics plans to expand into digital asset investments while continuing its cancer drug research. As part of this rebranding, the company changed its name to “Cypherpunk Technologies” and started trading under the ticker symbol “CYPH,” effective November 13.
Amaze Holdings (AMZE) – Amaze Holdings is a creator-driven commerce platform that provides comprehensive tools for effortless product creation and cutting-edge e-commerce solutions. On Friday, AMZE had a Dollar Volume of $126.34 million, while its stock price gained 1.8%.
Amaze’s shares gained due to several developments. The company reported a Q3 loss of $0.85 per share, wider than the prior year’s loss of $0.45 per share. However, revenue rose to $1.25 million, a significant increase from Q3FY24’s figure of $0.06 million. Moreover, Amaze announced the acquisition of The Food Channel’s assets for $650,000, payable in the form of a convertible promissory note issued by Amaze. This purchase helps Amaze expand by bringing its food creators together with The Food Channel’s brand to create a next-generation social commerce and entertainment platform.
Aspire Biopharma Holdings (ASBP) – Aspire Biopharma is an early-stage biopharmaceutical company focused on developing and marketing innovative sublingual drug delivery technology. On November 14, ASBP stock had a Dollar Volume of $57.97 million, with a 1.1% stock price gain.
ASBP announced an Equity Line of Credit (ELOC) agreement with Arena Business Solutions Global SPC II, Ltd. Under this agreement, Aspire Biopharma has the right to require Arena Business Solutions to purchase up to $100 million worth of ASBP stock. This arrangement provides Aspire Biopharma with flexible financing through the sale of its stock.
To find more penny stocks like these, you can take a look at TipRanks’ Penny Stock Screener tool. It shows a list of all penny stocks, their price movement, and other vital data.

