Orbimed Advisors Llc Insider Profile
74 Followers
Orbimed Advisors Llc, Shareholder at CTI BioPharma, holds 7.39M shares in Enliven Therapeutics (Ticker: ELVN), holds 625.00K shares in Q32 Bio (Ticker: QTTB), holds 2.67M shares in Sionna Therapeutics, Inc. (Ticker: SION). Most recently, Orbimed Advisors Llc Sold ― shares of Enliven Therapeutics on Jun 17, 2026 for an estimated value of $12.67M.
Profitable Transactions
138 out of 235 Profitable Transactions
Average Return
+7.70%
Average return per transaction
Time Frame
Compare to
Insider Holdings
A breakdown of Orbimed Advisors Llc's holdings
Insider Roles
Roles that Orbimed Advisors Llc holds in companies
Most Profitable Insider Trade
Stock:
Sientra
(SIENQ)
(SIENQ)
Rating:Informative Buy
Date:Oct 28, 2014 - Oct 28, 2015
Return:+570.60%
The most profitable trade made by Orbimed Advisors Llc
Orbimed Advisors Llc's Trading History
CTI BioPharma
Jan 11, 2021
―
Informative Sell
7.00M
$68.36M
Intercept Pharma
Jul 21, 2015
―
Uninformative Buy
―
$21.29M
Repare Therapeutics
Sep 08, 2021
―
Uninformative Sell
274.79K
$8.67M
Acutus Medical
Jul 21, 2021
Director, Ten Percent Owner
Informative Buy
15.00M
$16.81K
CalciMedica
Sep 29, 2020
Ten Percent Owner
Uninformative Buy
―
$3.14M
PMV Pharmaceuticals
Oct 27, 2025
Ten Percent Owner
Informative Sell
1.52M
$5.62M
Prelude Therapeutics
Apr 23, 2026
Director, Ten Percent Owner
Informative Buy
12.50M
$7.14M
Damora Therapeutics
Aug 17, 2023
Ten Percent Owner
Informative Sell
617.01K
$32.07M
Kinnate Biopharma
Apr 05, 2024
―
Uninformative Sell
―
$0.00
Terns Pharmaceuticals
Jul 17, 2024
―
Informative Sell
561.64K
$40.01M
Decibel Therapeutics
Feb 19, 2021
―
Uninformative Buy
―
$4.34M
Edgewise Therapeutics
Apr 04, 2025
Director, Ten Percent Owner
Informative Buy
10.00M
$16.34M
ImageneBio
Jul 30, 2025
Director
Uninformative Buy
208.19K
$4.64M
NeuroPace
May 16, 2025
Ten Percent Owner
Informative Sell
2.67M
$50.61M
Janux Therapeutics Inc
Dec 30, 2021
Director
Informative Sell
820.12K
$3.29M
Theseus Pharmaceuticals
Feb 14, 2024
―
Uninformative Sell
―
$0.00
Compass Therapeutics
Apr 11, 2025
Director, Ten Percent Owner
Informative Sell
5.68M
$30.74M
Third Harmonic Bio, Inc.
Sep 21, 2022
―
Uninformative Buy
―
$31.09M
Verona Pharma
May 15, 2023
―
Informative Sell
9.94M
$403.88M
Disc Medicine
Mar 26, 2025
Director
Informative Sell
310.48K
$13.21M
Turnstone Biologics Corp.
Aug 12, 2025
―
Uninformative Sell
―
$0.00
ARS Pharmaceuticals
Aug 28, 2024
Director
Informative Sell
1.09M
$79.98M
ArriVent BioPharma, Inc.
Jan 31, 2024
Director, Ten Percent Owner
Uninformative Buy
―
$48.04M
MBX Biosciences, Inc.
Feb 19, 2025
Director, Ten Percent Owner
Informative Buy
2.02M
$32.18M
Upstream Bio, Inc.
Oct 17, 2024
Director, Ten Percent Owner
Uninformative Buy
―
$28.47M
Traws Pharma
Apr 28, 2026
Ten Percent Owner
Informative Buy
998.21K
$1.02M
Sionna Therapeutics, Inc.
May 29, 2026
Director
Uninformative Sell
4.49K
$99.66M
Shattuck Labs
Sep 02, 2025
Director
Informative Buy
5.42M
$31.22M
Q32 Bio
Jun 01, 2026
Director, Ten Percent Owner
Informative Buy
15.00M
$7.44M
X4 Pharmaceuticals
Nov 20, 2017
Ten Percent Owner
Informative Buy
3.66M
$7.89M
scPharmaceuticals
Aug 15, 2024
―
Informative Buy
2.00M
$1.43M
Palvella Therapeutics
May 02, 2018
See Remarks, Ten Percent Owner
Informative Sell
6.35M
$4.40M
KALA BIO
Feb 12, 2018
Ten Percent Owner
Informative Buy
323.25K
$12.45M
Synlogic
Apr 22, 2021
Director
Uninformative Buy
5.00M
$2.62M
Armo Biosciences Inc
Jun 22, 2018
―
Uninformative Sell
205.95M
$205.86M
Adicet Bio
Apr 09, 2026
Ten Percent Owner
Informative Sell
674.85K
$7.48M
Audentes Therapeutics
Mar 12, 2018
―
Informative Sell
5.47M
$212.29M
Corvus Pharmaceuticals
Jul 01, 2025
Director, Ten Percent Owner
Uninformative Sell
4.88M
$85.34M
Rhythm Pharmaceuticals
May 24, 2018
See Remarks, Ten Percent Owner
Informative Sell
595.77K
$266.18M
Whitehawk Therapeutics
Jul 02, 2018
Director, Ten Percent Owner
Informative Buy
2.99M
$22.96M
Constellation Pharmaceuticals
Jul 24, 2018
―
Uninformative Buy
―
$14.21M
Xtant Medical Holdings
Apr 14, 2025
Ten Percent Owner
Informative Sell
30.71M
$0.00
Principia Biopharma
May 22, 2019
―
Informative Sell
30.25M
$160.65M
Guardant Health
Oct 11, 2018
Ten Percent Owner
Uninformative Buy
―
$1.18M
Logicbio Therapeutics
Oct 25, 2018
―
Uninformative Buy
―
$13.39M
Inspire Medical Systems
Aug 19, 2020
Director
Informative Sell
14.93M
$76.02K
Thoratec Corp
Dec 13, 2018
―
Uninformative Buy
―
$337.59M
Alector
Apr 16, 2020
Ten Percent Owner
Informative Sell
2.01M
$3.34M
Avedro
Feb 19, 2019
―
Uninformative Buy
―
$97.48M
Tricida
Nov 25, 2022
―
Informative Sell
2.21M
$0.00
Turning Point Therapeutics
Apr 24, 2019
―
Uninformative Buy
―
$154.11M
NextCure
May 13, 2019
Director, Ten Percent Owner
Informative Buy
5.25M
$5.48M
TELA Bio
Jul 02, 2024
Ten Percent Owner
Informative Sell
2.02M
$1.93M
89bio
Jan 27, 2022
―
Informative Sell
592.38K
$27.15M
Springworks Therapeutics
Sep 14, 2022
―
Informative Sell
4.92M
$263.14M
Prevail Therapeutics
Jun 26, 2019
―
Uninformative Buy
―
$317.92M
Alpine Immune Sciences
May 20, 2024
―
Uninformative Sell
―
$0.00
Sierra Oncology
Jul 01, 2022
―
Uninformative Sell
108.06M
$0.00
Arcutis Biotherapeutics
Jun 28, 2022
Ten Percent Owner
Informative Sell
7.29M
$10.88M
Passage Bio
Jun 26, 2025
Ten Percent Owner
Informative Sell
197.24K
$33.91M
Enliven Therapeutics
Jun 17, 2026
Ten Percent Owner
Informative Sell
12.67M
$333.24M
Keros Therapeutics
Dec 18, 2025
Director
Uninformative Sell
3.81M
$479.86K
Oric Pharmaceuticals
Mar 31, 2021
Director
Uninformative Sell
2.43M
$18.78M
Adaptimmune Therapeutics
Jun 06, 2018
Director
Informative Sell
253.63K
$196.05K
Viewray
Aug 20, 2018
Ten Percent Owner
Informative Sell
5.19M
―
Glaukos
Mar 06, 2018
Director
Informative Sell
26.79M
$0.00
Steadymed
Sep 07, 2018
―
Informative Sell
18.94M
$0.00
Nabriva Therapeutics
Dec 30, 2016
Director, Ten Percent Owner
Informative Buy
―
―
Spyre Therapeutics
Feb 21, 2017
Ten Percent Owner
Informative Buy
563.88K
$129.82M
Relypsa Inc
Jul 26, 2016
―
Informative Sell
129.39M
$236.73M
Mirati Therapeutics
Feb 05, 2015
―
Informative Buy
2.00M
$74.37M
Sientra
Oct 13, 2015
―
Informative Sell
1.72M
$427.50
Pacira Pharmaceuticals
Mar 13, 2012
Ten Percent Owner
Informative Sell
1.11M
$54.62M
Anthera Pharmaceuticals
Feb 01, 2013
Director
Informative Buy
3.76M
―
Otonomy
Nov 30, 2015
―
Informative Sell
1.94M
$212.76K
Insulet
―
Director
―
$228.67M
NxStage Medical
Dec 13, 2010
―
Informative Sell
53.25K
$80.71M
Loxo Oncology
Dec 12, 2017
―
Informative Sell
20.63M
$220.82M
Acceleron Pharma
Sep 26, 2013
―
Uninformative Buy
―
$103.12M
Supernus Pharmaceuticals
Feb 14, 2013
Ten Percent Owner
Informative Sell
2.28M
$36.26M
ChemoCentryx
Feb 15, 2012
―
Uninformative Buy
―
$47.23M
Albireo Pharma
Jun 11, 2009
―
Uninformative Sell
―
$65.60M
Sorrento Tech Inc
Oct 05, 2017
―
Informative Sell
137.10K
$19.75K
Athersys
Apr 29, 2011
Ten Percent Owner
Informative Sell
551.98K
―
Amarin
Sep 05, 2012
Director
Uninformative Sell
3.37M
$91.37K
Avanir Pharmaceuticals
―
―
―
―
Complete Genomics
―
―
―
―
Given Imaging Ltd
―
―
―
―
Volcano Corp
―
―
―
―
Ambit
May 24, 2013
―
Informative Buy
233.37K
―
List of latest transactions for each holding click on a transaction to see Orbimed Advisors Llc's performance on stock
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Orbimed Advisors Llc insider profile FAQ
What is the percentage of profitable transactions made by Orbimed Advisors Llc?
The percentage of profitable transactions made by Orbimed Advisors Llc is 59%.
What is the average return per transaction made by Orbimed Advisors Llc?
The average return per transaction made by Orbimed Advisors Llc is 7.70%.
What stocks does Orbimed Advisors Llc hold?
Orbimed Advisors Llc holds: CTIC, ICPT, RPTX, AFIB, CALC, PMVP, PRLD, DMRA, KNTE, TERN, DBTX, EWTX, IMA, NPCE, JANX, THRX, CMPX, THRD, VRNA, IRON, TSBX, SPRY, AVBP, MBX, UPB, TRAW, SION, STTK, QTTB, XFOR, SCPH, PVLA, KALA, SYBX, ARMO, ACET, ~BOLD, CRVS, RYTM, WHWK, CNST, XTNT, PRNB, GH, ~LOGC, INSP, ~THOR, ALEC, ~AVDR, TCDAQ, TPTX, NXTC, TELA, ETNB, SWTX, PRVL, ALPN, SRRA, ARQT, PASG, ELVN, KROS, ORIC, ADAPY, VRAYQ, GKOS, STDY, NBRVF, SYRE, RLYP, MRTX, SIENQ, PCRX, ANTH, OTIC, PODD, NXTM, LOXO, XLRN, SUPN, ~CCXI, ALBO, ROKA, ATHXQ, AMRN, AVNR, ~GNOM, GIVN, VOLC, ~AMBI stocks.
What was Orbimed Advisors Llc’s latest transaction?
Orbimed Advisors Llc latest transaction was an Informative Sell of $12.67M.
What was Orbimed Advisors Llc's most profitable transaction?
Orbimed Advisors Llc’s most profitable transaction was an Informative Buy of SIENQ stock on October 28, 2014. The return on the trade was 570.60%.
What is Orbimed Advisors Llc's role in CTI BioPharma?
Orbimed Advisors Llc's role in CTI BioPharma is Shareholder.
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