Prothena (PRTA) announced partner Roche (RHHBY) will advance prasinezumab, an investigational anti-alpha-synuclein antibody, into Phase III development in early-stage Parkinson’s disease. “This decision is informed by data from the Phase IIb PADOVA study and ongoing open-label extensions from both PADOVA and the Phase II PASADENA study,” the company said in a statement. The PASADENA and PADOVA OLE studies, which are evaluating the long-term safety and efficacy of prasinezumab in over 750 people with early-stage Parkinson’s disease, are ongoing, it added. Shares of Prothena are up 13%, or 67c, to $5.75 in premarket trading.
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