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Palisade Bio announces first patients dosed in Phase 1b study of PALI-2108

Palisade Bio (PALI) announced that the first patients have been dosed in its Phase 1b clinical study evaluating PALI-2108, a first-in-class, ileocolonic-targeted PDE4 inhibitor prodrug, for the treatment of fibrostenotic Crohn’s disease. Topline data are anticipated in the first quarter of 2026.

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