Moleculin Biotech reports assessment confirms no cardiotoxicity of Annamycin

Moleculin Biotech (MBRX) announced it has received a new independent assessment for the absence of cardiotoxicity in subjects treated with Annamycin, bringing the total number of Annamycin treated subjects reviewed by its independent expert to 90. Data from the most recently completed clinical trials’ subjects were made available to an expert in chemotherapy who is affiliated with a leading cancer research institute in assessing cardiotoxicity. After review of certain data, the independent expert concluded that there was no evidence of cardiotoxicity. This data is across five clinical trials treating acute myeloid leukemia and soft tissue sarcoma with Annamycin as a monotherapy and in combination with cytarabine and across multiple sites in the United States and the European Union. Most of these subjects were treated above the recommended lifetime maximum for other anthracyclines.