Knight Therapeutics (KHTRF) announced that its Mexican affiliate, Grupo Biotoscana de Especialidad, has submitted a marketing authorization application for CREXONT to COFEPRIS, the Mexican health regulatory agency, for the treatment of Parkinson’s disease, post-encephalitic parkinsonism, and parkinsonism that may follow carbon monoxide intoxication or manganese intoxication in adults. CREXONT is a novel, oral formulation of carbidopa/levodopa extended-release capsules for the treatment of Parkinson’s disease. In January 2024, Knight announced that it had entered into an agreement with Amneal Pharmaceuticals (AMRX) for the exclusive rights to seek regulatory approval and commercialize CREXONT in Canada and Latin America. In July 2025, Knight announced that CREXONT submission was accepted for review by Health Canada.
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