eXoZymes announces role in $9.2M Meta-PURE initiative

eXoZymes (EXOZ) announced its role in the Meta-PURE initiative, a $9.2M National Science Foundation funded project under the CFIRE program aimed at transforming the scalability and accessibility of cell-free systems to expand real-world applications. Led by Georgia Tech with a coalition of academic and industry groups, Meta-PURE will build a suite of standardized, interoperable ‘modules’ for cell-free biomanufacturing, enabling plug-and-play modules that can rapidly shift between use cases – from high-value nutraceuticals, to essential chemicals or pharmaceuticals. eXoZymes’ contribution builds on its ability to design complex enzyme cascades that operate outside of cells at unprecedented yields. “Our job in Meta-PURE is to build a cell-free power plant – an ATP-generating module that other teams can plug into to drive their own production modules,” said Dr. Paul Opgenorth, co-founder of eXoZymes and co-principal investigator on the award. Dr. Opgenorth continues, “By decoupling the power module from the production module, we’re enabling faster reaction times, greater product yields, and making the development of production modules more accessible for our partners across a broad spectrum of synthetic biology applications.”