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Crispr posts strong CTX310 data, says Chardan

Crispr Therapeutics (CRSP) reported encouraging updated Phase I data for its in vivo liver editing candidate CTX310, showing up to 82% reduction in triglycerides and 86% in LDL cholesterol, with safety in line with earlier findings, Chardan analyst Geulah Livshits tells investors in a research note. The company delayed guidance for its next program, CTX320 targeting Lp(a), to the first half of 2026, while full CTX310 data is expected in the second half of 2025. Despite questions around market demand for one-time gene editing in cardiovascular disease, Eli Lilly’s (LLY) $1B+ deal for Verve (VERV) supports investor confidence in the space, potentially boosting Crispr’s valuation, the firm says. Chardan has a Buy rating and $82 price target on Crispr Therapeutics shares.

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