“Cassava has made significant progress this year in leveraging our science to expand our portfolio. Our license with Yale University for intellectual property rights to potential treatments for certain rare diseases, including TSC-related epilepsy, has laid the groundwork for pursuing new therapeutic applications for simufilam. The appointments of Dr. Angelique Bordey as SVP, Neuroscience, and Dr. Jack Moore as SVP, Clinical Development, position us to advance toward a clinical trial program in TSC with diligence,” said Rick Barry, President and Chief Executive Officer of Cassava. “Our goal is to initiate the first clinical study in TSC-related epilepsy in first-half 2026, following the completion of necessary pre-clinical studies and the development of our regulatory strategy. With a favorable balance sheet, an enhanced team, and a new therapeutic indication for simufilam, we believe Cassava is well situated to move forward in 2025.”
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