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Bayer announces new drug application for gadoquatrane accepted for review by FDA

Bayer (BAYRY) announced that a new drug application for its investigational contrast agent gadoquatrane has been accepted for review by the FDA. The NDA for gadoquatrane has been filed for contrast-enhanced magnetic resonance imaging of the central nervous system and other body regions in adults and pediatric patients including neonates. If approved, gadoquatrane would become the lowest dose macrocyclic gadolinium-based contrast agent available in the U.S. The submitted dose is 0.04 mmol gadolinium per kilogram body weight, corresponding to a 60% reduction compared to macrocyclic GBCAs dosed at 0.1 mmol Gd/kg body weight.

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