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AstraZeneca’s Trixeo Aerosphere receives positive EU CHMP opinion

AstraZeneca’s (AZN) Trixeo Aerosphere, already licensed for the treatment of chronic obstructive pulmonary disease in adults, has received a positive opinion from the Committee for Medicinal Products for Human Use, CHMP, of the European Medicines Agency, endorsing it for use in the European Union, EU, with a next-generation propellant with near-zero Global Warming Potential. This fixed-dose triple-combination therapy, marketed as Breztri Aerosphere in the US, China and Japan, will now have a low carbon footprint comparable to inhaled medicines that do not require a propellant. Based on the CHMP positive opinion, AstraZeneca will now begin to transition its Trixeo supply to the next-generation propellant in Europe.

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