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Arvinas price target lowered to $14 from $24 at Piper Sandler

Piper Sandler lowered the firm’s price target on Arvinas (ARVN) to $14 from $24 by removing vepdegestrant value, while keeping an Overweight rating on the shares. The firm notes the Phase III VERITAC-2 trial of vepdegestrant met the primary mPFS endpoint vs. fulvestrant in 2nd-line ESR1-mutant ER+/HER2- mBC patients, and Arvinas will present data at ASCO on May 31st. Arvinas and Pfizer will submit regulatory filings in the second half of 2025, which could lead to monotherapy approval in 2026, however will not initiate Phase III combo trials.

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