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Amylyx doses first participant in Phase 3 LUCIDITY trial of avexitide

Amylyx (AMLX) Pharmaceuticals announced the first participant has been dosed in the pivotal Phase 3 LUCIDITY clinical trial of avexitide for post-bariatric hypoglycemia, or PBH. The trial will evaluate avexitide, a GLP-1 receptor antagonist with FDA Breakthrough Therapy Designation, in approximately 75 participants. Amylyx expects completion of recruitment in 2025, with topline data anticipated in the first half of 2026.

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