Piper Sandler analyst Edward Tenthoff raised the firm’s price target on Alnylam (ALNY) to $489 from $449 and keeps an Overweight rating on the shares. The firm notes AMVUTTRA sales of $685M in Q3 beat Street consensus driven by doubling of U.S. ATTR-CM revenues to $300M. Alnylam raised TTR revenue guidance to $2.475B-$2.525B in 2025, and Piper projects AMVUTTRA could grow to $3.9B in 2026.
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