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Xencor’s Promising Clinical Updates and Strong Efficacy Support Buy Rating

Xencor’s Promising Clinical Updates and Strong Efficacy Support Buy Rating

William Blair analyst Matt Phipps has maintained their bullish stance on XNCR stock, giving a Buy rating yesterday.

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Matt Phipps has given his Buy rating due to a combination of factors demonstrated in Xencor’s recent financial and clinical updates. The company reported promising initial Phase I data for its XmAb819 bispecific T-cell engager in clear cell renal cell carcinoma, showing a 25% overall response rate among efficacy-evaluable patients. This result indicates a strong initial efficacy profile with manageable safety concerns, as evidenced by low rates of grade 3 cytokine release syndrome.
Additionally, Xencor’s XmAb541 also showed encouraging preliminary efficacy, with three partial responses among nine patients. The deepening of response in one XmAb819 patient to 52% tumor shrinkage further underscores the potential of Xencor’s solid tumor TCE programs. These developments suggest significant value potential, supporting the Buy rating as Xencor continues to advance its clinical pipeline.

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