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Promising Clinical Data from Nurix Therapeutics’ BTK Degrader NX-5948 Supports Buy Rating

Promising Clinical Data from Nurix Therapeutics’ BTK Degrader NX-5948 Supports Buy Rating

In a report released today, Robert Burns from H.C. Wainwright reiterated a Buy rating on Nurix Therapeutics (NRIXResearch Report), with a price target of $36.00.

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Robert Burns has given his Buy rating due to a combination of factors related to the promising clinical data presented by Nurix Therapeutics. At the European Hematology 2025 annual meeting, Nurix showcased results from its BTK degrader, NX-5948, which is in Phase 1a/1b trials for patients with relapsed or refractory B-cell malignancies. The data revealed an impressive overall response rate (ORR) of 80.9% in chronic lymphocytic leukemia (CLL) patients, with notable response rates at various dosage levels, indicating the drug’s potential efficacy.
Additionally, the treatment showed an 84.2% ORR in patients with Waldenstrom macroglobulinemia, with responses deepening over time. The safety profile was manageable, with some occurrences of neutropenia, thrombocytopenia, and anemia, but no new cases of atrial fibrillation. These promising results, alongside the need for further follow-up to understand progression-free survival, support the reiterated Buy rating and a 12-month price target of $36.

In another report released on June 27, Oppenheimer also reiterated a Buy rating on the stock with a $32.00 price target.

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