In a report released today, Joseph Pantginis from H.C. Wainwright maintained a Buy rating on Biomea Fusion, with a price target of $4.00.
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Joseph Pantginis has given his Buy rating due to a combination of factors surrounding Biomea Fusion’s recent clinical trial outcomes and future potential. The company has reported promising 52-week results from its Phase 2 COVALENT-111 trial, which evaluated icovamenib in patients with Type 2 Diabetes (T2D). Despite some investor concerns about the limited number of patients and the absence of mechanistic biomarkers, the durability of icovamenib’s effect after treatment cessation suggests it could significantly impact the treatment landscape.
Biomea Fusion is actively addressing these concerns by planning further studies, such as the COVALENT-121 food effect study and the COVALENT-211 and COVALENT-212 trials targeting specific patient groups. These efforts indicate a strong commitment to advancing icovamenib’s clinical development and optimizing its therapeutic potential. The company’s focus on refining dosing criteria and exploring the drug’s interaction with GLP-1-based therapies underscores its strategic approach to overcoming current challenges and enhancing its market position.
In another report released on October 7, Citi also initiated coverage with a Buy rating on the stock with a $7.00 price target.

