Cathie Wood’s ARK Invest ETFs (exchange-traded funds) executed a series of trades on Wednesday, September 3, 2025, according to the funds’ daily disclosures. The trades reflect ARK’s continued confidence in the biotechnology sector, increasing its stake in gene-editing players, namely CRISPR Therapeutics (CRSP) and Intellia Therapeutics (NTLA). Meanwhile, ARK trimmed its holdings in TV streaming giant Roku (ROKU).
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Wood Continues to Expand Biotech Exposure
Wood continued to invest millions in some of her favorite biotechnology stocks. The largest trade of the day came in CRISPR, with the ARK Innovation ETF (ARKK) purchasing 40,041 shares valued at roughly $2.1 million. This follows Tuesday’s buy of 56,273 shares for $2.9 million, underscoring Wood’s growing confidence in the gene-editing company’s long-term potential.
ARKK also boosted its stake in clinical-stage biotech firm Intellia Therapeutics, adding 53,270 shares valued at about $607,000. The company has seen repeated purchases in recent days. Just yesterday, Wood picked up 169,686 shares of NTLA valued at $1.9 million, signaling a clear push into the gene-editing space.
At the same time, the ETF also picked up 105,139 shares of 10x Genomics (TXG) valued at $1.4 million, following a buy of 215,278 shares the prior day. The repeated purchases highlight ARK’s confidence in the company’s genomic analysis tools and their role in advancing precision medicine.
Year to date, CRISPR stock is up 39%, Intellia stock has surged 53%, and 10x Genomics stock has climbed 43%, reflecting strong momentum in the biotech space.
ARK Trims Stake in Roku
On the selling side, Wood trimmed 53,423 shares of Roku worth about $5.1 million. The ARKK ETF has been steadily cutting its Roku stake, including yesterday’s sale of 104,713 shares valued at roughly $10 million.
The pullback may signal caution or an effort to lock in gains, with Roku shares up nearly 34% over the past three months.
Let’s take a brief look at how all these stocks perform on TipRanks’ Stock Comparison Tool: