Using the TipRanks Stock Screener Tool, we identified three companies with high price-to-earnings (P/E) ratios, Strong Buy consensus ratings, and more than 60% upside potential over the next 12 months, making them compelling opportunities for growth-focused investors.
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An investment’s true worth comes from its expected future growth. A high P/E ratio can suggest overpricing, yet it often mirrors optimism about rapid earnings growth. The essential step is to compare current prices with the anticipated growth trajectory. Buying high P/E stocks means betting on companies with robust fundamentals, continuous innovation, and growing markets.
Here Are This Week’s High P/E Stocks
PaySign (PAYS) – PaySign has a P/E ratio of 37x, 173% higher than the sector average. On TipRanks, the average PaySign price target of $9 implies a massive 84% upside potential from current levels. Meanwhile, PAYS stock has gained 71% over the past year.
PaySign offers prepaid card solutions, patient assistance programs, digital banking tools, and full payment processing services tailored for businesses, consumers, and government entities. PaySign shows robust revenue growth, fueled by large gains in pharma patient affordability. Plus, its scalable platform supports 7.6 million cardholders across healthcare and plasma payments, driving lucrative margins.
Nebius Group (NBIS) – NBIS’ P/E ratio of 106x is astronomically higher than the sector average of 32.5x. On TipRanks, the average Nebius price target of $164.20 implies 67% upside potential from current levels. Meanwhile, NBIS stock has rocketed over 195% over the past year.
Nebius runs a full-stack AI cloud platform with Nvidia (NVDA) GPU (graphics processing unit) clusters for training and deploying AI models globally. The company offers efficient infrastructure for AI in healthcare, robotics, and finance, and is set to benefit from the booming AI demand, long-term contracts, cost edges, and strong growth potential. Nebius has also announced multi-billion-dollar deals with Microsoft (MSFT) and Meta (META), underscoring strong demand for its high-performance AI computing services.
Riot Platforms (RIOT) – RIOT has a P/E ratio of 44.9x, about 35% higher than the sector average. On TipRanks, the average Riot Platforms price target of $27.19 implies nearly 77% upside potential from current levels. Meanwhile, RIOT stock has surged over 27% over the past year.
Riot Platforms gives investors exposure to Bitcoin mining infrastructure and potential upside from scalable data-center assets. Plus, it plans to convert megawatts of power capacity into higher-margin compute assets over time. This combination can offer both growth leverage from crypto cycles and optionality from data-center opportunities.
To find more stocks like these, explore TipRanks’ Stock Screener Tool, which provides an updated list of stocks that can be filtered and scanned using various parameters.

