Vir Biotechnology, Inc. ((VIR)) announced an update on their ongoing clinical study.
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Study Overview: Vir Biotechnology, Inc. is conducting a Phase 2b study titled ‘A Phase 2b Randomized, Open-Label Study to Evaluate the Efficacy and Safety of Tobevibart+Elebsiran Combination Therapy Versus Bulevirtide in Participants With Chronic HDV Infection (ECLIPSE 3)’. The study aims to assess the efficacy and safety of a new combination therapy for chronic Hepatitis D Virus (HDV) infection, a significant health concern due to its severe liver complications.
Intervention/Treatment: The study tests two interventions: a combination of Tobevibart and Elebsiran, and Bulevirtide. Both Tobevibart and Elebsiran are administered via subcutaneous injection and are designed to treat chronic HDV infection.
Study Design: This interventional study employs a randomized, parallel assignment model with no masking, focusing on treatment as its primary purpose. Participants are divided into two groups: one receiving Tobevibart and Elebsiran for up to 240 weeks, and the other receiving Bulevirtide for 48 weeks followed by the combination therapy for an additional 192 weeks.
Study Timeline: The study began on August 19, 2025, with the most recent update submitted on October 1, 2025. These dates are crucial as they indicate the study’s progress and current recruitment status, which is ongoing.
Market Implications: This study update could positively impact Vir Biotechnology’s stock performance by showcasing its commitment to innovative treatments for viral infections. The success of this study could position Vir as a leader in HDV treatment, potentially influencing investor sentiment and affecting the competitive landscape in the pharmaceutical industry.
The study is ongoing, with further details available on the ClinicalTrials portal.