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Relay Therapeutics ( (RLAY) ) just unveiled an announcement.
Relay Therapeutics has revealed promising interim clinical data for RLY-2608, a novel treatment for PI3Kα-mutated, HR+, HER2- advanced breast cancer. The drug, an allosteric, pan-mutant, and isoform-selective PI3Kα inhibitor, showed a median progression-free survival of 9.2 months in heavily pre-treated patients. With favorable tolerability and significant tumor reduction observed, the data support the planned initiation of a pivotal study in 2025. Relay Therapeutics is also advancing with triplet regimens, including one with Pfizer’s atirmociclib, aiming for global commercialization partnerships to focus on their portfolio.
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