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Purple Biotech Reports Key Toxicology Milestone for CAPTN-3 Antibody IM1240

Story Highlights
  • Purple Biotech’s IM1240 showed up to 300-fold higher tolerated dosing with reduced immune toxicity.
  • Favorable pharmacokinetics support IM1240’s expanded therapeutic window and advancement toward human trials.
  • Looking for the best stocks to buy? Follow the recommendations of top-performing analysts.
Purple Biotech Reports Key Toxicology Milestone for CAPTN-3 Antibody IM1240

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Purple Biotech ( (PPBT) ) has provided an announcement.

On January 7, 2026, Purple Biotech reported that its tri-specific antibody IM1240, from the CAPTN-3 platform, successfully completed a non-human primate toxicology study, showing dosing tolerance up to 300 times higher than a non-capped comparator with markedly reduced immune-related toxicity and minimal cytokine release. The study also demonstrated a favorable pharmacokinetic profile, including increased systemic exposure and prolonged half-life attributed to IM1240’s capping design and albumin moiety, reinforcing the potential for an expanded therapeutic window and supporting its progression toward first-in-human clinical development with further advanced toxicological assessments planned.

The most recent analyst rating on (PPBT) stock is a Hold with a $0.65 price target. To see the full list of analyst forecasts on Purple Biotech stock, see the PPBT Stock Forecast page.

Spark’s Take on PPBT Stock

According to Spark, TipRanks’ AI Analyst, PPBT is a Neutral.

The score is held down primarily by the lack of revenue, ongoing losses, and negative free cash flow, indicating continued reliance on external funding. Technical indicators also point to a bearish trend with weak momentum. The main positive is the low-debt balance sheet, which reduces near-term leverage risk but does not offset weak operating fundamentals.

To see Spark’s full report on PPBT stock, click here.

More about Purple Biotech

Purple Biotech Ltd. (NASDAQ/TASE: PPBT) is a Rehovot, Israel-based clinical-stage oncology company developing first-in-class immunotherapies to overcome tumor immune evasion and drug resistance. Its lead CAPTN-3 platform comprises capped tri-specific antibodies that target tumor-associated antigens while engaging both T cells and NK cells, with lead candidates IM1240, targeting 5T4, advancing toward the clinic and IM1305, targeting TROP2, in preclinical development; the pipeline also includes CM24, a CEACAM1-blocking antibody that has shown improved outcomes in a Phase 2 pancreatic cancer study, and NT219, a dual IRS1/2 and STAT3 inhibitor in a Phase 2 head and neck cancer trial.

Average Trading Volume: 7,398,604

Technical Sentiment Signal: Sell

Current Market Cap: $6.45M

For detailed information about PPBT stock, go to TipRanks’ Stock Analysis page.

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