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PTC Therapeutics Posts Strong 2025 Results, Updates 2026 Outlook

Story Highlights
  • PTC’s 2025 unaudited revenue beat guidance, driven by a strong Sephience launch and robust Duchenne franchise.
  • With a $1.94 billion cash cushion, 2026 revenue guidance of $700–800 million and key FDA-aligned trials, PTC is funding growth while targeting cash-flow breakeven.
  • Looking for the best stocks to buy? Follow the recommendations of top-performing analysts.
PTC Therapeutics Posts Strong 2025 Results, Updates 2026 Outlook

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PTC Therapeutics ( (PTCT) ) has issued an announcement.

On January 12, 2026, PTC Therapeutics reported preliminary unaudited 2025 results showing approximately $823.4 million in total product and royalty revenue, above prior guidance, including $587.8 million in product revenue and $112.1 million from its newly launched Sephience, which generated $92.5 million in fourth-quarter sales alone and reached 946 patients worldwide by year-end. The company ended 2025 with about $1.94 billion in cash and securities, completed the sale of its remaining Evrysdi royalty stream for up to $300 million in consideration while retaining a potential $150 million milestone, advanced its pipeline with FDA alignment on a Phase 3 Huntington’s disease trial for votoplam and continued regulatory engagement on vatiquinone and Translarna, and issued 2026 guidance calling for $700 million to $800 million in product revenue and GAAP R&D and SG&A expenses of $775 million to $815 million, underscoring both strong launch momentum and sustained investment in late-stage programs as it moves toward cash-flow breakeven.

The most recent analyst rating on (PTCT) stock is a Buy with a $90.00 price target. To see the full list of analyst forecasts on PTC Therapeutics stock, see the PTCT Stock Forecast page.

Spark’s Take on PTCT Stock

According to Spark, TipRanks’ AI Analyst, PTCT is a Neutral.

The score is driven by strong operational momentum (high TTM revenue growth, strong margins, and positive earnings-call guidance around Sephience) and an inexpensive P/E. Offsetting factors are balance-sheet risk from negative equity/high leverage and only neutral technical momentum.

To see Spark’s full report on PTCT stock, click here.

More about PTC Therapeutics

PTC Therapeutics is a global biopharmaceutical company focused on discovering, developing and commercializing clinically differentiated medicines for children and adults with rare disorders, leveraging its ability to innovate and to globally commercialize products to support a diversified pipeline of transformative therapies.

Average Trading Volume: 1,544,995

Technical Sentiment Signal: Buy

Current Market Cap: $6.17B

For detailed information about PTCT stock, go to TipRanks’ Stock Analysis page.

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