Pacira’s Earnings Call Highlights Strategic Wins and Growth

Pacira ((PCRX)) has held its Q1 earnings call. Read on for the main highlights of the call.

Pacira BioSciences’ recent earnings call conveyed a positive sentiment, underscored by significant strategic achievements such as the EXPAREL patent settlement and robust sales growth. Despite these successes, the company faces some challenges, particularly in transitioning sales teams and adopting new reimbursement pathways.

EXPAREL Patent Settlement

Pacira successfully settled patent infringement litigation for EXPAREL, extending its exclusivity to 2039. This settlement eliminates the RDF royalty obligation, which is expected to benefit EXPAREL’s gross margins by a low single-digit percentage, marking a crucial strategic win for the company.

Growth in EXPAREL Sales

The first quarter saw a 7% increase in average daily EXPAREL sales and volumes compared to 2024, after adjusting for two fewer selling days in 2025. This growth highlights the strong demand and market position of EXPAREL.

PCRX-201 Progress

Pacira is making strides with PCRX-201, as patient dosing is underway in the Phase 2 ASCEND study for osteoarthritis of the knee. Early data is promising, suggesting potential for long-term pain relief, which could significantly impact the treatment landscape.

Stock Repurchase Program

In a move that signals confidence in its growth outlook, Pacira announced a $300 million stock repurchase program, effectively doubling its previous authorization. This decision reflects the company’s strong financial position and commitment to delivering shareholder value.

Strong Financial Performance

The company reported a substantial improvement in its consolidated first-quarter non-GAAP gross margin, which rose to 81% from 72% last year. This improvement was driven by enhanced manufacturing efficiencies and cost management.

ZILRETTA Sales Decline

ZILRETTA sales experienced a decline, falling to $23.3 million from $25.8 million in 2024. This decrease is attributed to the transition to new sales forces, indicating a temporary challenge in the sales strategy.

Challenges in Healthcare Reimbursement

Pacira is encountering logistical challenges in hospital systems adopting new pain reimbursement pathways. However, the company expects broad adoption in the second half of the year, which could alleviate current hurdles.

Forward-Looking Guidance

During the earnings call, Pacira provided substantial guidance reflecting its strong growth trajectory and strategic initiatives. The company introduced its “5×30” path to value creation, aimed at accelerating growth in its commercial business and advancing its innovative pipeline. Key achievements included the EXPAREL patent settlement and a 7% increase in sales, alongside a reaffirmed full-year 2025 revenue guidance of $725 million to $765 million.

In summary, Pacira’s earnings call reflected a generally positive sentiment, driven by strategic wins and robust financial performance. While challenges remain, particularly in sales transitions and reimbursement pathways, the company’s forward-looking strategies and initiatives indicate a promising outlook for future growth.