Novo Nordisk ((DE:NOVA)) announced an update on their ongoing clinical study.
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In a recent clinical study update, Novo Nordisk has completed a 40-week study titled ‘A Research Study to See How Well New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Levels in People With Type 2 Diabetes (T2D), Compared to Daily Insulin Glargine (COMBINE 4)’. The study aimed to evaluate the efficacy and safety of the new weekly drug IcoSema against the widely used daily insulin glargine in patients with type 2 diabetes inadequately controlled on oral anti-diabetic drugs.
The intervention involved two treatments: the experimental drug IcoSema, which combines insulin icodec and semaglutide administered weekly, and the daily administered insulin glargine. IcoSema is not yet available for prescription, unlike insulin glargine, which is already prescribed globally.
This interventional study was randomized with a parallel intervention model and had no masking, focusing primarily on treatment. Participants were randomly assigned to receive either IcoSema or insulin glargine over the course of 40 weeks.
The study began on February 15, 2024, and was completed by July 14, 2025. These dates are crucial as they mark the timeline from the study’s initiation to its completion, providing a framework for evaluating the study’s progress and results.
This update could influence Novo Nordisk’s stock performance and investor sentiment, especially as the company continues to innovate in diabetes treatment. Competitors in the diabetes treatment market may also feel the impact as Novo Nordisk potentially strengthens its position with new offerings.
The study has been completed, and further details can be accessed on the ClinicalTrials portal.