Novavax ((NVAX)) announced an update on their ongoing clinical study.
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Novavax has completed a Phase 3 study titled ‘A Phase 3 Study to Evaluate the Immunogenicity and Safety of Novavax COVID-19 Vaccine(s) as Second or Subsequent Booster After mRNA Vaccines in Individuals 18 to 49 Years of Age.’ The study aimed to assess the immune response and safety of Novavax’s vaccines as booster doses following mRNA vaccines. This research is significant as it explores the potential of Novavax’s vaccines to enhance immunity in adults who have already received mRNA vaccines.
The study tested two interventions: the NVX-CoV2373 vaccine and an updated COVID-19 vaccine, both administered as a single dose. These biological interventions are designed to boost immunity against COVID-19, utilizing Novavax’s proprietary Matrix-M adjuvant to enhance the immune response.
The study was interventional, with a randomized allocation and parallel intervention model. There was no masking involved, and the primary purpose was prevention. This straightforward design allows for clear assessment of the vaccine’s effectiveness as a booster.
The study began on March 28, 2023, and was completed with results first submitted on April 22, 2025. The last update was submitted on June 25, 2025. These dates are crucial as they mark the timeline of the study’s progression and the availability of its findings.
For investors, this update could positively influence Novavax’s stock performance, as successful results may enhance the company’s competitive position in the COVID-19 vaccine market. With ongoing demand for effective booster vaccines, Novavax’s progress could attract investor interest, especially in comparison to other vaccine developers.
The study is completed, with further details available on the ClinicalTrials portal.