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Metsera Announces Positive Phase 2b Trial Results

Story Highlights
  • Metsera announced positive Phase 2b trial results for MET-097i on September 29, 2025.
  • The trials showed significant weight loss and tolerability, leading to a planned Phase 3 program in late 2025.
  • Looking for the best stocks to buy? Follow the recommendations of top-performing analysts.
Metsera Announces Positive Phase 2b Trial Results

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The latest announcement is out from Metsera, Inc. ( (MTSR) ).

On September 29, 2025, Metsera, Inc. announced positive results from two Phase 2b trials, VESPER-1 and VESPER-3, for their GLP-1 receptor agonist MET-097i, which shows promise for monthly dosing. The trials demonstrated significant weight loss and class-leading tolerability, with minimal gastrointestinal side effects. These results pave the way for a Phase 3 program to start in late 2025, with ongoing studies to further explore MET-097i’s potential in weight management and type 2 diabetes treatment. The company is also developing additional clinical programs based on MET-097i.

The most recent analyst rating on (MTSR) stock is a Hold with a $57.00 price target. To see the full list of analyst forecasts on Metsera, Inc. stock, see the MTSR Stock Forecast page.

Spark’s Take on MTSR Stock

According to Spark, TipRanks’ AI Analyst, MTSR is a Underperform.

Metsera, Inc. faces significant challenges, primarily due to its lack of revenue and ongoing financial losses, which are critical concerns for long-term viability. The technical analysis indicates bearish momentum, reinforcing negative sentiment. Valuation metrics are limited, as the company does not have earnings or dividends. Despite a strong cash position, the high cash burn rate poses a risk. Overall, the lack of revenue and negative technical indicators weigh heavily on the stock’s potential.

To see Spark’s full report on MTSR stock, click here.

More about Metsera, Inc.

Average Trading Volume: 1,918,753

Technical Sentiment Signal: Strong Buy

Current Market Cap: $5.49B

For a thorough assessment of MTSR stock, go to TipRanks’ Stock Analysis page.

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