Inhibikase Therapeutics, Inc. ( (IKT) ) has released its Q2 earnings. Here is a breakdown of the information Inhibikase Therapeutics, Inc. presented to its investors.
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Inhibikase Therapeutics, Inc. is a clinical-stage pharmaceutical company focused on developing therapeutics for cardiopulmonary diseases, specifically Pulmonary Arterial Hypertension (PAH), utilizing its lead product candidate, IKT-001, a prodrug of imatinib mesylate.
In its second quarter of 2025, Inhibikase Therapeutics reported financial results and highlighted significant progress in advancing its lead product candidate, IKT-001, towards a Phase 2b clinical trial for PAH. The company’s efforts are focused on initiating this trial in the latter half of 2025, following the finalization of the study protocol.
Key financial metrics from the report include a net loss of $9.9 million for the quarter, an increase from the previous year’s $5.0 million, attributed to heightened research and development expenses, which rose to $5.3 million. The company’s cash position stood at $87.7 million as of June 30, 2025, a decrease from $97.5 million at the end of 2024. The upcoming IMPROVE-PAH study will involve 150 participants and aims to assess the efficacy of IKT-001 at varying dosages compared to a placebo.
Strategically, Inhibikase has been refining its clinical approach by engaging with key opinion leaders and conducting bioequivalence studies to ensure the optimal design of its Phase 2b trial. The study will focus on measuring changes in pulmonary vascular resistance and other secondary endpoints to validate the therapeutic potential of IKT-001.
Looking ahead, Inhibikase Therapeutics remains committed to advancing its clinical programs and is poised to initiate its pivotal Phase 2b trial in the second half of 2025. The company aims to leverage its research findings to enhance treatment options for PAH, potentially improving patient outcomes in this challenging therapeutic area.

