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Immunome Announces Positive Phase 3 Trial Results

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Immunome Announces Positive Phase 3 Trial Results

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Immunome ( (IMNM) ) has issued an update.

On December 15, 2025, Immunome announced positive topline results from its Phase 3 RINGSIDE trial of varegacestat in patients with progressing desmoid tumors. The trial demonstrated significant improvements in progression-free survival and objective response rate compared to placebo, with varegacestat showing an 84% reduction in the risk of disease progression or death. The company plans to submit a New Drug Application to the FDA in Q2 2026, positioning varegacestat as a potential new standard of care for desmoid tumors.

The most recent analyst rating on (IMNM) stock is a Buy with a $26.00 price target. To see the full list of analyst forecasts on Immunome stock, see the IMNM Stock Forecast page.

Spark’s Take on IMNM Stock

According to Spark, TipRanks’ AI Analyst, IMNM is a Neutral.

Immunome’s stock score is primarily influenced by its challenging financial performance, with significant losses impacting profitability. However, the technical analysis indicates strong bullish momentum, which is a positive factor. The valuation is negatively impacted by the negative P/E ratio and lack of dividend yield.

To see Spark’s full report on IMNM stock, click here.

More about Immunome

Immunome, Inc. is a clinical-stage biotechnology company focused on developing first-in-class and best-in-class targeted cancer therapies. The company is advancing a portfolio of therapeutics, including varegacestat, a gamma secretase inhibitor, and other innovative treatments targeting solid tumors.

Average Trading Volume: 1,447,645

Technical Sentiment Signal: Buy

Current Market Cap: $1.79B

See more data about IMNM stock on TipRanks’ Stock Analysis page.

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