HeartFlow, Inc. Reports Robust Q3 2025 Revenue Growth

HeartFlow, Inc. ( (HTFL) ) has released its Q3 earnings. Here is a breakdown of the information HeartFlow, Inc. presented to its investors.

HeartFlow, Inc., a leader in artificial intelligence technology for coronary artery disease, specializes in transforming cardiovascular care through its innovative HeartFlow One platform. The company leverages AI to create 3D models of the heart, offering actionable insights without invasive procedures.

In its third-quarter 2025 earnings report, HeartFlow, Inc. announced a significant 41% year-over-year increase in total revenue, reaching $46.3 million. The company also initiated its full-year 2025 revenue guidance, projecting between $173.0 million and $173.5 million.

Key financial highlights include a gross margin of 76.5% and a net operating loss of $15.1 million. HeartFlow’s recent successful IPO raised approximately $364.2 million, strengthening its balance sheet and positioning the company for future growth. Additionally, the launch of its next-generation HeartFlow Plaque Analysis and expanded insurance coverage by UnitedHealthcare and Cigna are expected to drive further market penetration.

Despite reporting a net loss of $50.9 million, the company showed improvement in non-GAAP metrics, with a reduced non-GAAP net loss of $13.2 million compared to the previous year. HeartFlow’s cash and cash equivalents totaled $291.2 million as of September 30, 2025, reflecting a robust financial position post-IPO.

Looking ahead, HeartFlow’s management remains optimistic about its growth prospects, supported by durable expansion in its core business and increasing adoption of its HeartFlow Plaque Analysis. The company is well-positioned to continue its leadership in the cardiovascular care market, driven by innovative technology and strategic investments.