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GSK’s Promising Phase 3 Study on Belimumab for Interstitial Lung Disease

GSK’s Promising Phase 3 Study on Belimumab for Interstitial Lung Disease

GlaxoSmithKline ((GSK)), GlaxoSmithKline plc (UK) ((GB:GSK)) announced an update on their ongoing clinical study.

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GlaxoSmithKline (GSK) is conducting a Phase 3 clinical study to evaluate the efficacy and safety of belimumab in adults with interstitial lung disease (ILD) associated with connective tissue disease (CTD). The study aims to determine if belimumab, when added to standard therapy, can stabilize or improve lung function and symptoms in affected individuals, while maintaining an acceptable safety profile.

The intervention being tested is belimumab, a biological treatment administered subcutaneously. It is designed to work alongside standard therapy to potentially enhance patient outcomes in ILD associated with CTD.

This randomized, double-blind, placebo-controlled study employs a parallel group design. Participants are randomly assigned to receive either belimumab or a placebo, in addition to their standard treatment. The study’s primary purpose is treatment-focused, with masking applied to participants, care providers, investigators, and outcomes assessors.

The study began on September 11, 2024, with its primary completion and estimated overall completion dates yet to be announced. The latest update was submitted on June 23, 2025, indicating ongoing recruitment and study activities.

The outcome of this study could significantly impact GSK’s stock performance and investor sentiment, especially if belimumab proves effective in treating ILD associated with CTD. This development could position GSK favorably against competitors in the biopharmaceutical industry.

The study is currently ongoing, with further details available on the ClinicalTrials portal.

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