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GH Research Sets January 5 Update on IND Status and Phase 3 Plans for Lead TRD Drug GH001

Story Highlights
  • GH Research will update investors January 5 on the IND status of GH001 and its global Phase 3 TRD program.
  • The IND and Phase 3 developments for inhaled mebufotenin candidate GH001 mark a pivotal step in GH Research’s bid to reshape TRD treatment.
  • Looking for the best stocks to buy? Follow the recommendations of top-performing analysts.
GH Research Sets January 5 Update on IND Status and Phase 3 Plans for Lead TRD Drug GH001

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GH Research ( (GHRS) ) just unveiled an announcement.

On January 2, 2026, GH Research PLC announced that it plans to provide an update on the status of its Investigational New Drug Application (IND) for its lead candidate GH001 with the U.S. Food and Drug Administration, along with details on its global pivotal Phase 3 program in treatment-resistant depression, on January 5, 2026. The planned update signals a key regulatory and clinical development milestone for the company, as progress on GH001’s IND and Phase 3 program will be central to its efforts to bring a potential practice-changing treatment for TRD to market and could materially influence its position in the competitive depression therapeutics landscape.

The most recent analyst rating on (GHRS) stock is a Hold with a $12.50 price target. To see the full list of analyst forecasts on GH Research stock, see the GHRS Stock Forecast page.

Spark’s Take on GHRS Stock

According to Spark, TipRanks’ AI Analyst, GHRS is a Neutral.

The score is held down primarily by weak operating fundamentals (no revenue, expanding losses, and sustained cash burn). Technical indicators also point to weak momentum with price below key moving averages and a negative MACD. Offsetting factors are a low-debt, equity-supported balance sheet that reduces solvency risk, but valuation is constrained by negative earnings and no dividend data.

To see Spark’s full report on GHRS stock, click here.

More about GH Research

GH Research PLC is a Dublin-based clinical-stage biopharmaceutical company focused on developing novel mebufotenin-based therapies for depression, with an initial emphasis on treatment-resistant depression (TRD). Its lead product candidate, GH001, uses a proprietary inhalation delivery approach and has shown promising Phase 2b results, including a statistically significant reduction in MADRS depression scores compared with placebo in TRD patients.

Average Trading Volume: 303,237

Technical Sentiment Signal: Buy

Current Market Cap: $787.8M

Find detailed analytics on GHRS stock on TipRanks’ Stock Analysis page.

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