Genprex ((GNPX)) announced an update on their ongoing clinical study.
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Genprex (GNPX) is conducting a clinical study titled ‘A Phase 1/2 Clinical Trial of Quaratusugene Ozeplasmid and Atezolizumab Maintenance Therapy in Patients With Extensive Stage Small Cell Lung Cancer (ES-SCLC).’ The study aims to evaluate the combination of quaratusugene ozeplasmid with atezolizumab as a maintenance therapy for ES-SCLC patients. This trial is significant as it explores a novel treatment approach for a challenging cancer type.
The interventions being tested are quaratusugene ozeplasmid and atezolizumab. Quaratusugene ozeplasmid is an experimental nonviral immunogene therapy designed to disrupt cancer cell growth and enhance immune response, while atezolizumab is a monoclonal antibody that blocks the PD-1/PD-L1 pathway to boost immune activity against cancer cells.
The study follows an interventional design with a non-randomized, sequential intervention model. It includes two phases: a dose selection phase (Phase 1) and a safety and efficacy evaluation phase (Phase 2). The primary purpose is treatment, and there is no masking involved.
The study began on January 19, 2023, with its primary completion and estimated completion dates not yet specified. The last update was submitted on October 14, 2025. These dates are crucial for tracking the study’s progress and anticipating future developments.
This clinical update could positively influence Genprex’s stock performance and attract investor interest, as it represents a potential breakthrough in ES-SCLC treatment. Investors should also consider the competitive landscape, as advancements in cancer therapies can shift market dynamics.
The study is ongoing, and further details are available on the ClinicalTrials portal.