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Cullinan Management Unveils Promising CLN-049 Clinical Data

Story Highlights
  • Cullinan Therapeutics announced new clinical data from its Phase 1 study of CLN-049.
  • CLN-049 showed significant anti-leukemic activity and a manageable safety profile in AML patients.
  • Looking for the best stocks to buy? Follow the recommendations of top-performing analysts.
Cullinan Management Unveils Promising CLN-049 Clinical Data

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Cullinan Management ( (CGEM) ) has shared an announcement.

On November 3, 2025, Cullinan Therapeutics announced promising new clinical data from its Phase 1 study of CLN-049, a novel FLT3xCD3 T cell engager, in patients with relapsed/refractory acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). The data, to be presented at the 67th American Society of Hematology Annual Meeting in December, showed significant anti-leukemic activity and a manageable safety profile, with a composite complete response rate of 31% at the highest dose level. These findings highlight CLN-049’s potential as a new treatment option for AML, a disease with limited current therapies, especially for patients with high-risk genetic features.

The most recent analyst rating on (CGEM) stock is a Buy with a $34.00 price target. To see the full list of analyst forecasts on Cullinan Management stock, see the CGEM Stock Forecast page.

Spark’s Take on CGEM Stock

According to Spark, TipRanks’ AI Analyst, CGEM is a Underperform.

Cullinan Management’s stock is facing significant challenges primarily due to its weak financial performance, characterized by persistent losses and negative cash flow. The technical analysis provides some short-term optimism, but the overall technical outlook remains bearish. The valuation is unattractive due to a negative P/E ratio and no dividend yield, indicating high risk for investors. The stock’s potential is heavily reliant on strategic changes and improved financial health.

To see Spark’s full report on CGEM stock, click here.

More about Cullinan Management

Cullinan Therapeutics, Inc. is a biopharmaceutical company focused on developing potential first- or best-in-class therapies for autoimmune diseases and cancer. The company leverages expertise in T cell engagers, with a clinical-stage pipeline aimed at delivering new standards of care.

Average Trading Volume: 868,153

Technical Sentiment Signal: Hold

Current Market Cap: $511.6M

For detailed information about CGEM stock, go to TipRanks’ Stock Analysis page.

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