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BioVaxys Cancer Vaccine Combo Shows Durable Responses in Recurrent Ovarian Cancer Trial

Story Highlights
  • BioVaxys’ MVP-S combo delivered strong response and disease control rates, especially in platinum-sensitive ovarian cancer patients.
  • The regimen outperformed standard chemotherapy in platinum-resistant disease and produced durable, immune-driven responses, supporting BioVaxys’s cancer vaccine strategy.
  • Looking for the best stocks to buy? Follow the recommendations of top-performing analysts.
BioVaxys Cancer Vaccine Combo Shows Durable Responses in Recurrent Ovarian Cancer Trial

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BioVaxys Technology ( (TSE:BIOV) ) just unveiled an update.

BioVaxys reported positive preliminary data from its investigator-initiated Phase 1b/2 PESCO trial evaluating a combination of its MVP-S cancer vaccine with pembrolizumab and low-dose cyclophosphamide in patients with recurrent epithelial ovarian cancer, demonstrating an overall response rate (ORR) of 24% and disease control rate (DCR) of 82% in high-grade endometrial cancer, with particularly strong outcomes in platinum-sensitive patients (40% ORR, 90% DCR). Importantly, the regimen also outperformed typical outcomes for standard single-agent chemotherapy in platinum-resistant disease, showed durable responses including a complete responder remaining disease-free for three years, and induced survivin-specific immune responses in most tested patients, underscoring the potential of BioVaxys’s DPX-based vaccine platform to enhance checkpoint inhibitor efficacy and address a population with historically poor treatment options.

Spark’s Take on TSE:BIOV Stock

According to Spark, TipRanks’ AI Analyst, TSE:BIOV is a Underperform.

BioVaxys Technology faces severe financial challenges, with no revenue and reliance on external financing, which heavily impacts its overall score. Technical analysis indicates weak momentum and a bearish trend, while the negative valuation metrics highlight the risks involved. However, the company is taking steps towards financial management and exploring new market opportunities, which could improve its future prospects.

To see Spark’s full report on TSE:BIOV stock, click here.

More about BioVaxys Technology

BioVaxys Technology Corp. is a clinical-stage biotechnology company developing advanced immunotherapies in oncology, infectious disease, allergy and other immune-related conditions, built around its DPX antigen delivery and immune-educating platform. Its lead oncology candidate, maveropepimut-S (MVP-S), is a DPX-based cancer vaccine designed to generate cytotoxic T-cell responses against survivin, a tumor-associated antigen overexpressed in ovarian and other cancers, positioning the company in the rapidly evolving field of cancer vaccine and checkpoint inhibitor combinations.

Average Trading Volume: 89,016

Technical Sentiment Signal: Sell

Current Market Cap: C$6.41M

For a thorough assessment of BIOV stock, go to TipRanks’ Stock Analysis page.

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